Use of corticosteroids to treat inflammation can lead to higher than normal blood glucose levels and, in longer-term usage, may lead to type 2 diabetes. If you already have diabetes, steroid medications, such as prednisone, typically cause a significant increase in blood glucose.

References

“Corticosteroids and Diabetes,” Diabetes.co.uk (updated on January 15, 2019). http://www.diabetes.co.uk/diabetes-medication/costicosteroids-and-diabetes.html (accessed on 8/3/2020).

Editorial Team. “Steroids and Diabetes: The Effect on Your Glucose Levels,” Medtronic (August 27, 2015). https://www.medtronicdiabetes.com/loop-blog/steroids-diabetes-effect-glucose-levels/ (accessed on 8/3/2020).

Cowley, Goretti; medically reviewed by Alan Carter, PharmD. “What is the link between prednisone and diabetes?” Medical News Today (March 28, 2019). https://www.medicalnewstoday.com/articles/317015 (accessed on 8/3/2020).

The Effect of Topical Steroids on Blood Glucose Profile in Diabetic Patients
https://www.longdom.org/open-access/the-effect-of-topical-steroids-on-blood-glucose-profile-in-diabetic-patients-2155-9570.1000133.pdf